bsm-51162M

DATASHEET

Host: Mouse

Target Protein: FMR1

Clonality: Monoclonal

Isotype: IgM

Entrez Gene: 2332

Swiss Prot: Q06787

Source: This FMR1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 20-48 amino acids from human FMR1.

Purification: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene.

Size: 100ul

Concentration: 0.5ug/ul

Predicted Molecular Weight: 71

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.