bsm-51068M

DATASHEET

Host: Mouse

Target Protein: MAP3K11

Clonality: Monoclonal

Isotype: IgM

Entrez Gene: 4296

Swiss Prot: Q16584

Source: This MAP3K11 monoclonal antibody is generated from mouse immunized with MAP3K11 recombinant protein.

Purification: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

Activates the JUN N-terminal pathway. Required for serum-stimulated cell proliferation and for mitogen and cytokine activation of MAPK14 (p38), MAPK3 (ERK) and MAPK8 (JNK1) through phosphorylation and activation of MAP2K4/MKK4 and MAP2K7/MKK7. Plays a role in mitogen-stimulated phosphorylation and activation of BRAF, but does not phosphorylate BRAF directly. Influences microtubule organization during the cell cycle.

Size: 100ul

Concentration: 0.5ug/ul

Predicted Molecular Weight: 93

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.