bsm-43589R

DATASHEET

Host: Rabbit

Target Protein: CD86

Immunogen Range: 24-239/329

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 56822

Swiss Prot: O35531

Source: Recombinant human CD86 protein

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

Storage: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Background:

This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011].

Size: 100ul

Concentration: 1ug/ul

Applications: WB(WB=1:500-2000)
Flow-Cyt(Flow-Cyt=1ug/Test)
ICC/IF(ICC/IF=1:50-200)

Predicted Molecular Weight: 37

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.