bsm-33345M-Cy7 [Conjugated Primary Antibody]
TGF beta 1(6B9) Monoclonal Antibody, Cy7 Conjugated
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Mouse

Target Protein: TGF beta 1

Clonality: Monoclonal

Isotype: IgG1

Entrez Gene: 7040

Swiss Prot: P01137

Source: KLH conjugated synthetic peptide derived from human TGF beta 1

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form composed of a TGFB1 homodimer. The mature peptide may also form composed of a TGFB1 homodimer. The mature peptide may also form composed of a TGFB1 homodimer. The mature peptide may also form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease.

Conjugation: Cy7

Excitation/ Emission: 743nm/767nm

Size: 100ul

Concentration: 1ug/ul

Applications: IF(ICC)(1:50-200)

Predicted Molecular Weight: 12.8/44 kDa


Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Mengna Duan. et al. Epidermal stem cell-derived exosomes promote skin regeneration by downregulating transforming growth factor-1 in wound healing. Stem Cell Res Ther. 2020 Dec;11(1):1-11Read more>>
  • Yue Feng. et al. METTL3/METTL14 transactivation and m6A-dependent TGF-1 translation in activated Kupffer cells. Cell Mol Gastroenter. 2021 MayRead more>>
  • Leiming Sun. et al. Isoliquiritigenin attenuates acute renal injury through suppressing oxidative stress, fibrosis and JAK2/STAT3 pathway in streptozotocin-induced diabetic rats. Bioengineered. 2021;12(2):11188-112Read more>>
  • Yanan Hao. et al. Alginate Oligosaccharides Repair Liver Injury by Improving Anti-Inflammatory Capacity in a Busulfan-Induced Mouse Model. INT J MOL SCI. 2023 Jan;24(4):3097Read more>>
  • Xiao Zebin. et al. Desmoplastic stroma restricts T cell extravasation and mediates immune exclusion and immunosuppression in solid tumors. NAT COMMUN. 2023 Aug;14(1):1-21Read more>>
  • etl Seher Uysal. et al. Investigation of healing strategies in a rat corneal opacity model with polychromatic light and stem cells injection. J PHOTOCH PHOTOBIO B. 2024 Apr;253:112874Read more>>
  • Xusen Wang. et al. 3D printing of Rg3-loaded hydrogel scaffolds: anti-inflammatory and scar-formation related collagen inhibitory effects for scar-free wound healing. J MATER CHEM B. 2024 ApRead more>>
  • Mya Thandar. et al. Mesenchymal stem cells derived from adipose tissue and umbilical cord reveal comparable efficacy upon radiation-induced colorectal fibrosis in rats. AM J CANCER RES. 2024 Apr 15;14(4):1594-1608Read more>>
  • Shan Zhong. et al. Electrical and immune stimulation-based hydrogels synergistically realize scarless wound healing via amplifying endogenous electrophysiological function and promoting Macrophage Phenotype-Switching. CHEM ENG J. 2024 Jul;491:152048Read more>>