bsm-30304M-PE

DATASHEET

Host: Mouse

Target Protein: Tumor necrosis factor receptor superfamily member 8

Clonality: Monoclonal

Isotype: IgG1/Kappa

Entrez Gene: 943

Swiss Prot: P28908

Purification: Affinity purified by Protein G

Storage Buffer: 0.01M PBS, 0.5%BSA, 0.02% Proclin300

Storage: Store at 2-8℃. Protect from light. Avoid freezing.

Background:

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

Size: 25T,100T

Concentration: n/a

Applications: FCM(10μl per million cells in 100μl staining volume)

Predicted Molecular Weight: 62

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.