bsm-30297M-PE

DATASHEET

Host: Mouse

Target Protein: T-cell surface glycoprotein CD8 alpha chain

Clonality: Monoclonal

Isotype: IgG1/Kappa

Entrez Gene: 24930

Swiss Prot: P07725

Purification: Affinity purified by Protein G

Storage Buffer: 0.01M PBS, 0.5%BSA, 0.02% Proclin300

Storage: Store at 2-8℃. Protect from light. Avoid freezing.

Background:

CD8 (cluster of differentiation 8) is a transmembrane glycoprotein that serves as a co-receptor for the T cell receptor (TCR). Like the TCR, CD8 binds to a major histocompatibility complex (MHC) molecule, but is specific for the class I MHC protein. There are two isoforms of the protein, alpha and beta, each encoded by a different gene. The CD8 co-receptor is predominantly expressed on the surface of cytotoxic T cells, but can also be found on natural killer cells, cortical thymocytes, and dendritic cells.The CD8 molecule is a marker for cytotoxic T cell population. It is expressed in T cell lymphoblastic lymphoma and hypo-pigmented mycosis fungoides.

Size: 25T,100T

Concentration: n/a

Applications: FCM(10μl per million cells in 100μl staining volume)

Predicted Molecular Weight: 27

Cross Reactive Species: Rat

For research use only. Not intended for diagnostic or therapeutic use.