DATASHEET
Host:
Mouse
Target Protein:
H-2 class I histocompatibility antigen, Q7 alpha chain
Clonality:
Monoclonal
Isotype:
IgG2a/Kappa
Entrez Gene:
15018
Swiss Prot:
P14429
Purification:
Affinity purified by Protein G
Storage Buffer:
0.01M PBS, 0.5%BSA, 0.02% Proclin300
Storage:
Store at 2-8℃. Protect from light. Avoid freezing.
Background:
Predicted to enable several functions, including 14-3-3 protein binding activity; TAP binding activity; and signaling receptor binding activity. Acts upstream of or within cellular response to interferon-gamma and embryo implantation. Predicted to be located in several cellular components, including bounding membrane of organelle; cell surface; and endoplasmic reticulum. Predicted to be part of MHC class I protein complex and MHC class Ib protein complex. Predicted to be active in external side of plasma membrane and extracellular space. Is expressed in several structures, including brain; genitourinary system; hemolymphoid system gland; liver; and small intestine. Human ortholog(s) of this gene implicated in asthma; hepatitis C; and occupational asthma. Orthologous to human HLA-E (major histocompatibility complex, class I, E); HLA-F (major histocompatibility complex, class I, F); and HLA-G (major histocompatibility complex, class I, G). [provided by Alliance of Genome Resources, Apr 2022]