bsm-30282H-PE

DATASHEET

Host: Hamster

Target Protein: Killer cell lectin-like receptor 3

Clonality: Monoclonal

Isotype: IgG1

Entrez Gene: 16634

Swiss Prot: Q64329

Purification: Affinity purified by Protein G

Storage Buffer: 0.01M PBS, 0.5%BSA, 0.02% Proclin300

Storage: Store at 2-8℃. Protect from light. Avoid freezing.

Background:

KLRA3 (also known as Ly49C) is a member of the LY49 family of receptors in Natural Killer (NK) cells that bind to major histocompatibility complex (MHC) class 1. These proteins are classified as either activating or inhibitory receptors based on whether they possess an immunoreceptor tyrosine-based inhibitory motif (ITIM) in their cytoplasmic region (for inhibitory receptors), or an immunoreceptor tyrosine-based activation motif (ITAM) that transmits activating signals resulting in phosphorylation of several substrates. KLRA3 is thought to be an inhibitory receptor, recognizing peptide–receptive H-2Kb.

Size: 25T,100T

Concentration: n/a

Applications: FCM(10l per million cells in 364l staining volume)

Cross Reactive Species: Mouse

For research use only. Not intended for diagnostic or therapeutic use.