bsm-30269A-PE [Flow Cytometry]
mouse CD105/PE
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Host: Rat

Target Protein: Endoglin

Clonality: Monoclonal

Isotype: IgG2a/Kappa

Entrez Gene: 13805

Swiss Prot: Q63961

Purification: Affinity purified by Protein G

Storage Buffer: 0.01M PBS, 0.5%BSA, 0.02% Proclin300

Storage: Store at 2-8℃. Protect from light. Avoid freezing.

Background:

Enables protein homodimerization activity and transforming growth factor beta binding activity. Involved in several processes, including circulatory system development; positive regulation of cell differentiation; and regulation of gene expression. Acts upstream of or within circulatory system development and positive regulation of angiogenesis. Located in endothelial microparticle. Is expressed in several structures, including brain; cardiovascular system; extraembryonic vascular system; and lung. Used to study arteriovenous malformations of the brain and hereditary hemorrhagic telangiectasia. Human ortholog(s) of this gene implicated in arteriovenous malformation; arteriovenous malformations of the brain; breast cancer; hereditary hemorrhagic telangiectasia; and intracranial aneurysm. Orthologous to human ENG (endoglin). [provided by Alliance of Genome Resources, Apr 2022]

Size: 25T,100T

Concentration: n/a

Applications: FCM(10l per million cells in 151l staining volume)

Predicted Molecular Weight: 70


Cross Reactive Species: Mouse

For research use only. Not intended for diagnostic or therapeutic use.