bsm-30252A-APC-CY7 [Flow Cytometry]
mouse CD45.1/APC-Cy7
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Host: Rat

Target Protein: Receptor-type tyrosine-protein phosphatase C

Clonality: Monoclonal

Isotype: IgG1/Kappa

Entrez Gene: 19264

Swiss Prot: P06800

Purification: Affinity purified by Protein G

Storage Buffer: 0.01M PBS, 0.5%BSA, 0.02% Proclin300

Storage: Store at 2-8℃. Protect from light. Avoid freezing.

Background:

Enables several functions, including heparan sulfate proteoglycan binding activity; heparin binding activity; and protein tyrosine phosphatase activity. Involved in several processes, including lymphocyte differentiation; positive regulation of macromolecule metabolic process; and regulation of signal transduction. Acts upstream of or within several processes, including lymphocyte differentiation; positive regulation of lymphocyte activation; and regulation of protein phosphorylation. Located in external side of plasma membrane; focal adhesion; and membrane raft. Is expressed in several structures, including 3rd branchial arch; alimentary system; cardiovascular system; hemolymphoid system; and placenta. Used to study systemic lupus erythematosus. Human ortholog(s) of this gene implicated in hepatitis C; multiple sclerosis; severe combined immunodeficiency; and severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-positive, Nk cell-positive. Orthologous to human PTPRC (protein tyrosine phosphatase receptor type C). [provided by Alliance of Genome Resources, Apr 2022]

Size: 25T,100T

Concentration: n/a

Applications: FCM(10l per million cells in 263l staining volume)

Cross Reactive Species: Mouse

For research use only. Not intended for diagnostic or therapeutic use.