bsm-30249A-PE-CY5 [Flow Cytometry]
mouse CD40/PE-Cy5
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Host: Rat

Target Protein: Tumor necrosis factor receptor superfamily member 5

Clonality: Monoclonal

Isotype: IgG2a/Kappa

Entrez Gene: 21939

Swiss Prot: P27512

Purification: Affinity purified by Protein G

Storage Buffer: 0.01M PBS, 0.5%BSA, 0.02% Proclin300

Storage: Store at 2-8℃. Protect from light. Avoid freezing.

Background:

Predicted to enable antigen binding activity; protein domain specific binding activity; and ubiquitin protein ligase binding activity. Involved in B cell mediated immunity; CD40 signaling pathway; and cellular calcium ion homeostasis. Acts upstream of or within several processes, including defense response to other organism; positive regulation of B cell activation; and positive regulation of interleukin-12 production. Located in external side of plasma membrane and intracellular membrane-bounded organelle. Part of CD40 receptor complex. Is expressed in several structures, including alimentary system; brain; hemolymphoid system gland; liver and biliary system; and reproductive system. Human ortholog(s) of this gene implicated in several diseases, including Kawasaki disease; autoimmune disease (multiple); end stage renal disease; hyperimmunoglobulin syndrome (multiple); and non-Hodgkin lymphoma (multiple). Orthologous to human CD40 (CD40 molecule). [provided by Alliance of Genome Resources, Apr 2022]

Size: 25T,100T

Concentration: n/a

Applications: FCM(10l per million cells in 257l staining volume)

Predicted Molecular Weight: 30


Cross Reactive Species: Mouse

For research use only. Not intended for diagnostic or therapeutic use.