bsm-30230A-PE [Flow Cytometry]
human IL-6/PE
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Host: Rat

Target Protein: Interleukin-6

Clonality: Monoclonal

Isotype: IgG1/Kappa

Entrez Gene: 3569

Swiss Prot: P05231

Purification: Affinity purified by Protein G

Storage Buffer: 0.01M PBS, 0.5%BSA, 0.02% Proclin300

Storage: Store at 2-8℃. Protect from light. Avoid freezing.

Background:

This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Elevated levels of the encoded protein have been found in virus infections, including COVID-19 (disease caused by SARS-CoV-2). [provided by RefSeq, Aug 2020]

Size: 25T,100T

Concentration: n/a

Applications: FCM(10l per million cells in 121l staining volume)

Predicted Molecular Weight: 23


Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.