bsm-30223M-PE

DATASHEET

Host: Mouse

Target Protein: DNA nucleotidylexotransferase

Clonality: Monoclonal

Isotype: IgG1/Kappa

Entrez Gene: 1791

Swiss Prot: P04053

Purification: Affinity purified by Protein G

Storage Buffer: 0.01M PBS, 0.5%BSA, 0.02% Proclin300

Storage: Store at 2-8℃. Protect from light. Avoid freezing.

Background:

This gene is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq, Jul 2008]

Size: 25T,100T

Concentration: n/a

Applications: FCM(10l per million cells in 129l staining volume)

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.