Host: Mouse
Target Protein: E-selectin
Clonality: Monoclonal
Isotype: IgG1 κ
Entrez Gene: 6401
Swiss Prot: P16581
Purification: affinity Purified by Protein G.
Storage Buffer: 0.01M PBS, 0.5%BSA, 0.02% Proclin300
Storage: Store at 2-8℃. Protect from light. Avoid freezing.
Background:
The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis. [provided by RefSeq, Jul 2008]
Size: 25T
Concentration: n/a
Applications: FCM()
Predicted Molecular Weight: 65
Cross Reactive Species: Human
For research use only. Not intended for diagnostic or therapeutic use.