bsm-30138M-FITC

DATASHEET

Host: Mouse

Target Protein: Tumor necrosis factor ligand superfamily member 6

Clonality: Monoclonal

Isotype: IgG1/Kappa

Entrez Gene: 356

Swiss Prot: P48023

Purification: Affinity purified by Protein G

Storage Buffer: 0.01M PBS, 0.5%BSA, 0.02% Proclin300

Storage: Store at 2-8℃. Protect from light. Avoid freezing.

Background:

This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2014]

Size: 25T,100T

Concentration: n/a

Applications: FCM(10μl per million cells in 100μl staining volume)

Predicted Molecular Weight: 31

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.