bsm-30119M-PE

DATASHEET

Host: Mouse

Target Protein: Integrin alpha-6

Clonality: Monoclonal

Isotype: IgG2a/Kappa

Entrez Gene: 3655

Swiss Prot: P23229

Purification: Affinity purified by Protein G

Storage Buffer: 0.01M PBS, 0.5%BSA, 0.02% Proclin300

Storage: Store at 2-8℃. Protect from light. Avoid freezing.

Background:

The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2/HER2 signaling. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]

Size: 25T,100T

Concentration: n/a

Applications: FCM(10μl per million cells in 100μl staining volume)

Predicted Molecular Weight: 21/124

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.