bs-9861R-Biotin [Conjugated Primary Antibody]
Titin Polyclonal Antibody, Biotin Conjugated
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: Titin

Immunogen Range: 2601-2800/34350


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 7273

Swiss Prot: Q8WZ42

Source: KLH conjugated synthetic peptide derived from human Titin (Ig-like 15 domain)

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

Key component in the assembly and functioning of vertebrate striated muscles. By providing connections at the level of individual microfilaments, it contributes to the fine balance of forces between the two halves of the sarcomere. The size and extensibility of the cross-links are the main determinants of sarcomere extensibility properties of muscle. In non-muscle cells, seems to play a role in chromosome condensation and chromosome segregation during mitosis. Might link the lamina network to chromatin or nuclear actin, or both during interphase.

Conjugation: Biotin

Excitation/ Emission: N/A

Size: 100ul

Concentration: 1ug/ul

Applications: ELISA(1:500-1000)
IHC-P(1:200-400)

Predicted Molecular Weight: 3816


Cross Reactive Species: Human
Mouse
Rat
Others

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Kanda et al. Detection of titin fragments in urine in response to exercise-induced muscle damage. (2017) PLoS.One. 12:e0181623Read more>>
  • Ying Wang. et al. Long noncoding RNA TTN-AS1 facilitates tumorigenesis and metastasis by maintaining TTN expression in skin cutaneous melanoma. Cell Death Dis. 2020 Aug;11(8):1-13Read more>>
  • Hongyun Wei. et al. Titin as a potential novel therapeutic target in colorectal cancer. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 2023 JulRead more>>
VALIDATION IMAGES