DATASHEET
Host:
Rabbit
Target Protein:
LAPTM4A
Immunogen Range:
101-200/233
Clonality:
Polyclonal
Isotype:
IgG
Entrez Gene:
9741
Swiss Prot:
Q15012
Source:
KLH conjugated synthetic peptide derived from human LAPTM4A
Purification:
Purified by Protein A.
Storage Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage:
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Background:
Lysosomal-associated transmembrane protein 4A (LAPTM4A), also known as Golgi 4-transmembrane spanning transporter MTP, is a 233 amino acid protein belonging to the LAPTM5/LAPTM5 transporter family. LAPTM4A is subcellularly localized to the intracytoplasmic membrane and has the potential to reside in intracellular membrane-bound compartments. LAPTM4A is thought to function as a transporter of nucleosides and/or nucleoside derivatives between the cytosol and the lumen of intracellular compartments. LAPTM4A is predicted to have four transmembrane domains, with the C-terminal domain being required for retention of the protein within intracellular membranes.
May function in the transport of nucleosides and/or nucleoside derivatives between the cytosol and the lumen of an intracellular membrane-bound compartment
VALIDATION IMAGES
Mouse lung lysates probed with LAPTM4A Polyclonal Antibody, Unconjugated (bs-9562R) at 1:1000 dilution and 4˚C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.
Lane 1: Mouse Uterus lysates; Lane 2: Mouse Ovary lysates probed with LAPTM4A Polyclonal Antibody, Unconjugated (bs-9562R) at 1:1000 dilution and 4˚C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.