bs-8845R [Primary Antibody]
Synaptophysin Polyclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: Synaptophysin

Immunogen Range: 151-250/313


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 6855

Swiss Prot: P08247

Source: KLH conjugated synthetic peptide derived from human Synaptophysin

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity.

Size: 100ul

Concentration: 1ug/ul

Applications: IHC-P(1:200-400)

Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • in Liu. et al. Nicotinamide Improves Cognitive Function in Mice With Chronic Cerebral Hypoperfusion. Front Neurol. 2021; 12: 596641Read more>>
  • Yue-Ming Zhang. et al. Long-term environmental enrichment overcomes depression, learning, and memory impairment in elderly CD-1 mice with maternal sleep deprivation exposure. FRONT AGING NEUROSCI. 2023; 15: 117725Read more>>
  • Heng Yang. et al. miR-665 overexpression inhibits the apoptosis of luteal cells in small ruminants suppressing HPGDS. THERIOGENOLOGY. 2023 Aug;206:4Read more>>
  • Yue-Ming Zhang. et al. Sleep deprivation aggravates lipopolysaccharide-induced anxiety, depression and cognitive impairment: The role of pro-inflammatory cytokines and synaptic plasticity-associated proteins. J NEUROIMMUNOL. 2024 Jan;386:578252Read more>>
  • Yue-Ming Zhang. et al. Resveratrol prevents cognitive deficits induced by sleep deprivation via modulating sirtuin 1 associated pathways in the hippocampus. J BIOCHEM MOL TOXIC. 2024 Mar;38(4):e23698Read more>>
  • Yue-Ming Zhang. et al. Melatonin improves maternal sleep deprivation-induced learning and memory impairment, inflammation, and synaptic dysfunction in murine male adult offspring. BRAIN BEHAV. 2024 May;14(5):e3515Read more>>
  • Meng-Ying Zhang. et al. Subsequent maternal sleep deprivation aggravates cognitive impairment by modulating hippocampal neuroinflammatory responses and synaptic function in maternal isoflurane-exposed offspring mice. BRAIN BEHAV. 2024 Jun;14(7):e361Read more>>
VALIDATION IMAGES

Paraformaldehyde-fixed, paraffin embedded (human brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Synaptophysin) Polyclonal Antibody, Unconjugated (bs-8845R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.