DATASHEET
Host:
Rabbit
Target Protein:
BDKRB1
Immunogen Range:
161-260/353
Clonality:
Polyclonal
Isotype:
IgG
Entrez Gene:
623
Swiss Prot:
P46663
Source:
KLH conjugated synthetic peptide derived from human BDKRB1
Purification:
Purified by Protein A.
Storage Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage:
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Background:
This is a receptor for bradykinin. Could be a factor in chronic pain and inflammation.
PRODUCT SPECIFIC PUBLICATIONS
- Liu et al. Kinin B1 receptor as a novel, prognostic progression biomarker for carotid atherosclerotic plaques. (2017) Mol.Med.Rep. 16:8930-8936Read more>>
- Gao et al. The Combination of Human Urinary Kallidinogenase and Mild Hypothermia Protects Adult Rats Against Hypoxic-Ischemic Encephalopathy-Induced Injury by Promoting Angiogenesis and Regeneration. (2018) Front.Aging.Neurosci. 10:196Read more>>
- Shen Y et al. Elevated bradykinin receptor type 1 expression in postpartum acute myometritis: Possible involvement in augmented interstitial edema of the atonic gravid uterus. J Obstet Gynaecol Res. 2019 Jun 10.Read more>>
- Qin L et al. Bradykinin 1 receptor blockade subdues systemic autoimmunity, renal inflammation, and blood pressure in murine lupus nephritis. Arthritis Res Ther. 2019 Jan 8;21(1):12. Read more>>
- Debargha Basuli. et al. Kinin B1 Receptor Mediates Renal Injury and Remodeling in Hypertension. Front Med-Lausanne. 2021; 8: 780834Read more>>
- Dong Zhang. et al. Aldh1a1 and Scl25a30 in diaphragmatic dysfunction:. EXP BIOL MED. Exp Biol Med. 0;()Read more>>
- Wojciech Dyga. et al. The Role of Bradykinin Receptors in Hereditary Angioedema Due to C1-Inhibitor Deficiency. INT J MOL SCI. 2022 Jan;23(18):10332Read more>>
- usco Indiara. et al. Kinin B1 and B2 receptors mediate cancer pain associated with both the tumor and oncology therapy using aromatase inhibitors. SCI REP-UK. 2023 Mar;13(1):1-16Read more>>
- Jeimy Katherine Torres-Mndez. et al. Nicotinamide Prevents Diabetic Brain Inflammation via NAD+-Dependent Deacetylation Mechanisms. NUTRIENTS. 2023 Jan;15(14):3083Read more>>
- atista Carolina. et al. Kinin B1 receptor and TLR4 interaction in inflammatory response. INFLAMM RES. 2024 Jul;:1-18Read more>>
VALIDATION IMAGES
Formalin-fixed and paraffin embedded human lung cancer labeled with Rabbit Anti-BDKRB1 Polyclonal Antibody, Unconjugated (bs-8675R) at 1:200 followed by conjugation to the secondary antibody and DAB staining
Lane 1: Mouse Liver tissue lysates; Lane 2: Human SiHa cell lysates; Lane 3: Human LOVO cell lysates; Lane 4: Human K562 cell lysates; Lane 5: Human U251 cell lysates probed with BDKRB1 Polyclonal Antibody, Unconjugated (bs-8675R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.