bs-83409C
[Life Science]
(R)-(+)Etomoxir Na
DATASHEET
Formulation White solid
Storage: -20°C
Product Information:
Etomoxir (828934-41-4) is an irreversible inhibitor of mitochondrial carnitine palmitoyl transferase 1 (CPT1).1 It is widely used to study fatty acid oxidation. Etomoxir has been investigated as a therapeutic agent for heart disease2, diabetes3, and cancer4,5. Use of etomoxir in concentrations greater than 5 µM induces acute production of ROS with associated evidence of severe oxidative stress in proliferating T cells indicating a loss of specificity for CTP1 at these concentrations.6 200 µM etomoxir inhibited complex I of the electron transport chain.7
Description:
CAS Number: 828934-41-4<br></br>Chemical Name: Carnitine palmitoyltransferase inhibitor<br></br>Molecular Weight: 320.74<br></br>Formula: C15H18ClO4·Na<br></br>Solubility: DMSO (5 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: 98% by HPLC, NMR (Conforms)
Size: 25mg,5mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.