bs-83120C
[Life Science]
Metolazone
DATASHEET
Formulation White solid
Storage: RT
Product Information:
Activates mitochondrial unfolded protein response (UPRMT) and -increases C. elegans lifespan.4 Clinically useful diuretic that inhibits the thiazide-sensitive Na+-Cl– cotransporter (NCC) (IC50 = 0.3 µM rat), blocking sodium reabsorption.2,3 Metolazone also inhibits human carbonic anhydrase isoforms VII, XII, and XIII with nanomolar potency.4.
Description:
CAS Number: 17560-51-9<br></br>Chemical Name: 7-Chloro-1,2,3,4-tetrahydro-2-methyl-3-(2-methylphenyl)-4-oxo-6-quinazolinesulfonamide<br></br>Molecular weight: 365.83<br></br>Formula: C16H16ClN3O3S<br></br>Solubility: DMSO (up to 36 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: 98% by HPLC NMR (Conforms)
Size: 50 mg, 250 mg50 mg, 250 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.