bs-83118C
[Life Science]
CID1067700
DATASHEET
Formulation beige solid
Storage: -20°C
Product Information:
A specific competitive inhibitor of nucleotide binding to Rab7, an endosome-localized small GTPase.1 It interferes with the Rab7-RILP interaction, locking the GTPase in an inactive conformation.2 Impairs B cell class switching and plasma cell survival dampening, the pathogenic autoantibody response in lupus.3 Inhibits the Arf-like small GTPase Arl8b, blocking cellular egress of b-coronaviruses (SARS-CoV-2) which utilize a lysosomal exocytosis pathway.4
Description:
CAS Number: 314042-01-8<br></br>Chemical Name: 2-[[(benzoylamino)thioxomethyl]amino]-4,7-dihydro-5,5-dimethyl-5H-thieno[2,3-c]pyran-3-carboxylic acid<br></br>Molecular weight: 390.48<br></br>Formula: C18H18N2O4S2<br></br>Solubility: DMSO (40 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: 98% by TLC NMR (Conforms)
Size: 25mg,5mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.