bs-83117C
[Life Science]
Biotin-isoxazole
DATASHEET
Formulation White solid
Storage: -20°C
Product Information:
Exposure of cell or tissue lysates to biotin-isoxazole precipitates hundreds of RNA-binding proteins with significant overlap to the constituents of RNA granules.1,2 In one study roughly 580 nuclear proteins were identified as being precipitated by B-Isox including TAF15, RNA polymerase II (largest subunit), numerous subunits of the mediator complex as well as a variety of enzymes involved in epigenetic modification of histones.3 SR domains were found to be the determinant that facilitates B-Isox precipitation.4 Also allows for the fractionation / isolation of SG-associated proteins and RNA precipitates.5
Description:
CAS Number: 1377605-22-5<br></br>Chemical Name: 6-(5-(Thiophen-2-yl)isoxazole-3-carboxamido)hexyl 5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoate<br></br>Molecular weight: 520.66<br></br>Formula: C24H32N4O5S2<br></br>Solubility: DMSO (30 mg/ml)<br></br>Physical Properties: beige solid<br></br>Purity: 98% by TLC nMR (Conforms)
Size: 1 mg, 5 mg 5 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.