bs-83106C
[Life Science]
Phenylhexyl isothiocyanate
DATASHEET
Formulation White solid
Storage: -20°C
Product Information:
Isothiocyanate constituents of cruciferous vegetables are potent chemopreventive agents for carcinogen-induced cancers in rodents.1 PHITC was the most potent in a series of synthetic arylalkyl isothiocyanates at inhibition of tumorigenicity by NNK, a tobacco-derived nitrosamine, in a mouse model.2 It was also found to induce apoptosis and inhibit leukemia cell growth in vivo3 and was shown to have dual function as a histone deacetylase inhibitor and hypomethylating agent4. PHITC was also shown to restore the activity of mutant p53 and reactivate the p53 pathway in human myeloid leukemia M2 cells.5
Description:
CAS Number: 133920-06-6<br></br>Chemical Name: 6-Isothiocyanatohexylbenzene<br></br>Molecular weight: 219.35<br></br>Formula: C13H17NS<br></br>Solubility: DMSO (25 mg/ml)<br></br>Physical Properties: Colorless to pale yellow liquid<br></br>Purity: >98% by TLC NMR (Conforms)
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.