DATASHEET
Formulation
Off-white solid
Storage:
-20°C
Product Information:
An allosteric agonist at the Drosophila RDL GABA receptor.1,2 Also acts as an agonist at glutamate-gated chloride channels in insects.3 Mutations (specifically a G326E substitution) in the glutamate-gated chloride channel 3 (GluCl3) in phytophagous mites abolishes agonist activity resulting in resistance.4 Commercially used as an acaricide.
Description:
CAS Number: 1799297-76-9<br></br>Chemical Name: Milbemycin A3: (6R,25R)-5-O-demethyl-28-deoxy-6,28-epoxy-25-methyl-milbemycin B
Milbemycin A4: (6R,25R)-5-O-demethyl-28-deoxy-6,28-epoxy-25-ethyl-milbemycin B<br></br>Molecular weight: 542.71 (A4)<br></br>Formula: C32H46O7 (A4)<br></br>Solubility: DMSO (20 mg/ml) Ethanol (40 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: >98% HPLC; Milbemectin is a mixture of Milbemycin A3 (~30%) and Milbemycin A4 (~70%)
NMR (Conforms)