bs-83104C
[Life Science]
HET0016
DATASHEET
Formulation White solid
Storage: -20°C
Product Information:
HET0016 (339068-25-6) inhibits 20-hydroxyeicosatetraenoic acid (20-HETE) biosynthesis via omega oxidation of arachidonic acid mediated by CYP4A and 4F (IC50=8.9 nM in human renal microsomes).1 It displays neuroprotective effects in a rat model of traumatic brain injury via inhibition of neuronal pyroptosis.2 HET0016 attenuates cerebral ischemia-reperfusion injury3 as well as oxidative injury and peripheral nerve damage in type-2 diabetic mice4. It alleviates myocardial oxidative stress5 and restores endothelial function suggesting therapeutic potential in obesity-associated vascular disease6.
Description:
CAS Number: 339068-25-6<br></br>Chemical Name: N-Hydroxy-N’-(4-butyl-2-methylphenyl)formamidine<br></br>Molecular weight: 206.29<br></br>Formula: C12H18N2O<br></br>Solubility: DMSO (20 mg/ml)<br></br>Physical Properties: Off-white solid<br></br>Purity: >98% by HPLC NMR (Conforms)
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.