bs-83094C
[Life Science]
IM-12
DATASHEET
Formulation White or off-white solid
Storage: -20°C
Product Information:
A potent and selective inhibitor of glycogen synthase kinase 3 (GSK-3) IC50=53 nM which induces neuronal differentiation.1 Activates the Wnt--catenin signaling pathway and attenuates tissue plasminogen activator-induced hemorrhagic transformation after acute ischemic stroke in animal models.2 Promoted hair follicle growth in vitro and antagonized the inhibition of hair follicles by dihydrotestosterone.3 Down-regulates Sox9 expression in limbal epithelial stem/progenitor cells leading to increased differentiation.4
Description:
CAS Number: 1129669-05-1<br></br>Chemical Name: 3-(4-Fluorophenylethylamino)-1-methyl-4-(2-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione<br></br>Molecular weight: 377.41<br></br>Formula: C22H20FN3O2<br></br>Solubility: DMSO (50 mg/ml)<br></br>Physical Properties: Yellow solid<br></br>Purity: 98% by HPLC NMR (Conforms)
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.