DATASHEET
Formulation
Off-white solid
Storage:
-20°C
Product Information:
A potent and selective inhibitor of Src family kinases Lck and Src, IC50=2 and 6 nM respectively.1,2 Also inhibits SIK, IC50=10, 22 and 60 nM for SIK 1, 2 and 3 respectively.3 May be used along with PD-325901 and CHIR-99021 to support self-renewal of naïve human embryonic stem cells.4
Description:
CAS Number: 837422-57-8<br></br>Chemical Name: N-(2,4-dimethoxyphenyl)-N-[2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]-carbamic acid , 2,6-dimethylphenyl ester<br></br>Molecular weight: 568.67<br></br>Formula: C32H36N6O4<br></br>Solubility: DMSO (60 mg/ml)<br></br>Physical Properties: White or off-white solid<br></br>Purity: 98% by HPLC NMR (Conforms)