bs-83090C
[Life Science]
BAM15
DATASHEET
Formulation Pale-yellow solid
Storage: -20°C
Product Information:
A mitochondrial protonophore uncoupler with fewer off-target effects (EC50 = 270 nM in L6 myoblast mitochondria.)1,2 Compared to FCCP, an uncoupler of equal potency, BAM15 stimulates a higher maximum rate of mitochondrial respiration and does not depolarize the plasma membrane.2 Stimulates energy expenditure, protects against obesity and improves glycemic control in rodent models.3 Reverses diet-induced obesity and insulin resistance in mice.4 Attenuates transportation-induced apoptosis in iPS-differentiated retinal tissue.5
Description:
CAS Number: 210302-17-3<br></br>Chemical Name: N5,N6-bis(2-Fluorophenyl)-[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine<br></br>Molecular weight: 340.29<br></br>Formula: C16H10F2N6O<br></br>Solubility: DMSO (35 mg/ml)<br></br>Physical Properties: Pale-yellow solid<br></br>Purity: 98% by TLC NMR (Conforms)
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.