DATASHEET
Formulation
White or off-white solid
Storage:
-20°C
Product Information:
Endogenous antioxidant.1,2 Treatment with alpha-lipoic acid increased hepatic nuclear Nrf2 levels, induced Nrf2-mediated gene transcription, and reversed age-related decline in hepatic glutathione levels in a rat model.3 It is an essential cofactor required for catalysis by multiple mitochondrial enzymes including pyruvate dehydrogenase, α-ketoglutarate dehydrogenase and branched-chain ketoacid dehydrogenase among others.4 It has shown efficacy as a treatment in diabetic neuropathy.5
Description:
CAS Number: 1077-28-7<br></br>Chemical Name: (±)-1,2-Dithiolane-3-pentanoic acid<br></br>Molecular weight: 206.32<br></br>Formula: C8H14O2S2<br></br>Solubility: DMSO (30 mg/ml)<br></br>Physical Properties: Pale-yellow solid<br></br>Purity: >98% by TLC NMR (Conforms)