bs-83085C
[Life Science]
SSAA09E1
DATASHEET
Formulation Pale-yellow solid
Storage: -20°C
Product Information:
SSAA09E1 (433212-75-0) is an inhibitor of SARS coronavirus (SARS-CoV) replication by blocking viral entry (EC50=6.7mM). SSAA09E1 was discovered by screening a chemical library for blocking of entry of HIV-1 pseudotyped with SARS-CoV surface glycoprotein S. The compound acts via inhibition of cathepsin L(IC50=5.33 mM), a host protease required for processing of SARS-S during viral entry. Cathepsin B is not inhibited.1 The compound was also shown to inhibit tyrosinase (IC50=0.14 mM).2
Description:
CAS Number: 433212-75-0<br></br>Chemical Name: [(Z)-1-Thiophene-2-ylethylideneamino]thiourea<br></br>Molecular weight: 199.29<br></br>Formula: C7H9N3S2<br></br>Solubility: DMSO (100 mg/ml); ethanol (10 mg/ml with warming<br></br>Physical Properties: Beige solid<br></br>Purity: >98% by TLC NMR (Conforms)
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.