DATASHEET
Formulation
Pale-yellow solid
Storage:
-20°C
Product Information:
A naturally occurring alkaloid from Stephania cepharantha Hayata which possesses a number of pharmacological activities.1 Attenuates LPS-induced expression of TNF-, IL-6 and IL-1 in macrophages and inhibits NF-B activation.2 Induces mitophagy possibly by acting at GPR30 in hepatocellular carcinoma.3 Inhibits autophagosome-lysosome fusion and autophagy by downregulation of MYO1C an actin-based motor protein.4 Potently inhibits replication of SARS CoV-2 and homologous viruses.5
Description:
CAS Number: 481-49-2<br></br>Chemical Name: <br></br>Molecular weight: 606.71<br></br>Formula: C37H38N2O6<br></br>Solubility: DMSO (35 mg/ml) Ethanol (20 mg/ml)<br></br>Physical Properties: Pale-yellow solid<br></br>Purity: 95% by HPLC NMR (Conforms)