bs-83080C
[Life Science]
GKT-137831
DATASHEET
Formulation White solid
Storage: -20°C
Product Information:
NADPH oxidase, NOX1/4 inhibitor (Ki = 100-150 nM).1 Inhibits erastin-stimulated ROS production.2 Potentiates immunotherapy by overcoming cancer-associated fibroblast- mediated CD8+ T-cell exclusion.3 Reduces ROS production in LPS-stimulated platelets in a mouse model.4 Reduces subarachnoid hemorrhage-induced neuronal death.5 Potent inhibitor of experimental liver fibrosis in mouse models.6
Description:
CAS Number: 1218942-37-0<br></br>Chemical Name: 2-(2-Chlorophenyl)-4-[3-(dimethylamino)phenyl]-5-methyl-1H-pyrazolo[4,3-c]pyridine-3,6(2H,5H)-dione <br></br>Molecular weight: 394.85<br></br>Formula: C21H19ClN4O2<br></br>Solubility: DMSO (65 mg/ml)<br></br>Physical Properties: Pale-yellow solid<br></br>Purity: 98% by TLC NMR (Conforms)
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.