bs-83075C
[Life Science]
GRL-0617
DATASHEET
Formulation Off-white solid
Storage: -20°C
Product Information:
GRL-0617 is a potent (IC50 = 600 nM) noncovalent inhibitor of severe acute respiratory syndrome-coronavirus papain-like protease (SARS-CoV PLpro). GRL0617 inhibited SARS-CoV viral replication in Vero E6 cells with no cytotoxicity (EC50 = 15 µM). Inactive against human DUB-like proteases HAUSP, USP18, UCH-L1, UCH-L3, and PLP2.
Description:
CAS Number: 1093070-16-6<br></br>Chemical Name: 5-Amino-2-methyl-N-(1R-naphthalen-1-yl-ethyl)benzamide<br></br>Molecular weight: 304.39<br></br>Formula: C20H20N2O <br></br>Solubility: DMSO (>30 mg/ml) Ethanol (>15 mg/ml)<br></br>Physical Properties: Beige solid<br></br>Purity: 99% by HPLC NMR (Conforms)
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.