DATASHEET
Formulation
Off-white or pale yellow solid
Storage:
-20°C
Product Information:
Toll-like receptor 7 (TLR7) agonist (EC50 = 290 nM in a HEK293 cell line reporter assay; IFNα MEC 3 nM, 100 fold selectivity over TNFα activation).1 Displays significant antiviral activity via immune activation against HIV2,3, Hepatitis B4,5, Norovirus6, and enterovirus7.
Description:
CAS Number: 1228585-88-3<br></br>Chemical Name: 4-Amino-2-butoxy-8-[[3-(pyrrolidine-1-ylmethyl)phenyl]methyl]-5,7-dihydropteridin-6-one<br></br>Molecular weight: 410.52<br></br>Formula: C22H30N6O2<br></br>Solubility: DMSO (10 mg/ml)<br></br>Physical Properties: Off-white solid<br></br>Purity: 98% by HPLC NMR (Conforms)