DATASHEET
Formulation
Tan solid
Storage:
-20°C
Product Information:
UCPH-101 is a potent (IC50 = 660 nM) and selective inhibitor of the excitatory amino acid transporter 1 (EAAT1).1,2 It induced cell death in glioblastoma cells via intracellular glutamate accumulation. UCPH-101 also significantly increased survival in glioma-bearing mice.3
Description:
CAS Number: 1118460-77-7<br></br>Chemical Name: 2-Amino-4-(4-methoxyphenyl)-7-naphthalen-1-yl-5-oxo-4,6,7,8-tetrahydrochromene-3-carbonitrile<br></br>Molecular weight: 422.48<br></br>Formula: C27H22N2O3 <br></br>Solubility: DMSO (10 mg/ml)<br></br>Physical Properties: Off-white solid<br></br>Purity: 98% by HPLC NMR (Conforms)