bs-83050C
[Life Science]
GSK872
DATASHEET
Formulation White solid
Storage: -20°C
Product Information:
GSK872 is a potent (IC50 = 1.8nM domain binding; IC50 = 1.3 nM kinase activity) and selective inhibitor of receptor interacting protein 3 (RIP3).1 It is able to prevent necroptosis, virus-induced necrosis, and TLR3-induced necrosis.1,2 GSK872 can induce Caspase8-mediated apoptosis at higher concentrations (e.g.3 µM).2
Description:
CAS Number: 1346546-69-7<br></br>Chemical Name: N-(6-Propan-2-ylsulfonylquinolin-4-yl)-1,3-benzothiazol-5-amine<br></br>Molecular weight: 383.49<br></br>Formula: C19H17N3O2S2<br></br>Solubility: DMSO (>25 mg/ml)<br></br>Physical Properties: Off-white or pale yellow solid<br></br>Purity: 98% by HPLC NMR (Conforms)
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.