DATASHEET
Formulation
Off-white solid
Storage:
-20°C
Product Information:
Potent (IC50 = 2.1 nM ADP-Glo assay; 4.8 nM Oxaloacetate coupled enzyme assay) allosteric inhibitor of ATP-citrate lyase.1 NDI-091143 suppressed growth and clonogenic ability in thyroid cancer cell lines FTC-133 and 8505C.2 It also synergistically potentiated the cytotoxicity of sorafenib.2
Description:
CAS Number: 2375840-87-0<br></br>Chemical Name: Methyl 3-Chloro-5-[(2,4-difluoro-5-phenylphenyl)sulfamoyl]-4-hydroxybenzoate<br></br>Molecular weight: 453.84<br></br>Formula: C20H14ClF2NO5S<br></br>Solubility: DMSO (>50 mg/ml)<br></br>Physical Properties: Off-white solid<br></br>Purity: >98% by HPLC NMR (Conforms)