bs-83043C
[Life Science]
LDN-192960 HCl
DATASHEET
Formulation Yellow solid
Storage: -20°C
Product Information:
LDN-192960 is a potent inhibitor of Haspin (IC50 = 10 nM), DYRK2 (IC50 = 2 nM), and DYRK3 (IC50 = 19 nM).1,2 It induced cytotoxicity and growth inhibition in multiple myeloma and triple negative breast cancer cells and triple negative breast cancer mouse allo/xenografts via partial inhibition of 26S proteasome activity.3
Description:
CAS Number: 184582-62-5<br></br>Chemical Name: 3-(2,7-Dimethoxyacridin-9-yl)sulfanylpropan-1-amine dihydrochloride<br></br>Molecular weight: 401.35<br></br>Formula: C18H20N2O2S·2HCl <br></br>Solubility: DMSO (>25 mg/ml) Water (2 mg/ml)<br></br>Physical Properties: Yellow solid<br></br>Purity: >98% by HPLC NMR (Conforms)
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.