DATASHEET
Formulation
Yellow solid
Storage:
-20°C
Product Information:
NVP-BGJ398 is a potent and selective pan-FGFR inhibitor (IC50 = 0.9nM, 1.4 nM, 1.0 nM, and 60 nM for FGFR1,2,3,4 respectively).1 It has also been used in a mouse model of Achondroplasia (most common form of dwarfism) to correct pathological hallmarks of this condition.2
Description:
CAS Number: 872511-34-7<br></br>Chemical Name: 3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-(6-{[4-(4-ethyl-1-piperazinyl)phenyl]amino}-4-pyrimidinyl)-1-methylurea<br></br>Molecular weight: 560.48<br></br>Formula: C26H31Cl2N7O3<br></br>Solubility: DMSO (5 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: 99% by HPLC NMR (Conforms)