bs-83029C
[Life Science]
NU7441
DATASHEET
Formulation Off-white solid
Storage: -20°C
Product Information:
NU7441 is a potent (IC50 = 13 nM) and selective ATP-competitive inhibitor of DNA-dependent protein kinase (DNA-PK).1,2 It increased the toxicity of ionizing radiation and etoposide on SW620 human colon cancer lines via impeding of DNA double-strand break repair.3 NU7441 also increased the radio/chemosensitivity of various other cancer cell lines.3-6
Description:
CAS Number: 503468-95-9<br></br>Chemical Name: 8-Dibenzothiophen-4-yl-2-morpholin-4-ylchromen-4-one<br></br>Molecular weight: 413.49<br></br>Formula: C25H19NO3S<br></br>Solubility: DMSO (10 mg/ml)<br></br>Physical Properties: Off-white to beige solid<br></br>Purity: 98% by TLC NMR (Conforms)
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.