bs-83026C
[Life Science]
AZD1152-HQPA
DATASHEET
Formulation Yellow solid
Storage: -20°C
Product Information:
AZD1152-HQPA is a potent and highly selective inhibitor of Aurora B.1 Aurora B Ki = 0.36 nM; Aurora A Ki = 1,369 nM.2 It inhibits the growth of tumors in multiple cancer models.3-6 Excessive ROS generation7 and upregulated tumor suppressor miRNAs8 have been proposed as a novel mechanisms of cytotoxicity of AZD1152-HQPA.
Description:
CAS Number: 722544-51-6<br></br>Chemical Name: 3-[[7-[3-[Ethyl(2-hydroxyethyl)amino]propoxy]-4-quinazolinyl]amino-N-(3-fluorophenyl)-1H-pyrazole-5-acetamide<br></br>Molecular weight: 507.56<br></br>Formula: C26H30FN7O3<br></br>Solubility: DMSO (15 mg/ml)<br></br>Physical Properties: Yellow solid<br></br>Purity: 98% by HPLC NMR (Conforms)
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.