bs-83018C
[Life Science]
Fruquintinib
DATASHEET
Formulation White solid
Storage: -20°C
Product Information:
Fruquintinib is a potent and highly selective inhibitor of VEGFR kinase (IC50’s: VEGFR1= 33 nM, VEGFR2 = 35 nM, VEGFR3 = 0.5 nM).1 It potently inhibited VEGF/VEGFR signaling and cell proliferation in HUVECs and HLECs and prevented angiogenesis in vitro. Fruquintinib is currently is several clinical trials against metastatic colorectal cancer2 and nonsquamous non-small-cell lung cancer3.
Description:
CAS Number: 1194506-26-7<br></br>Chemical Name: 6-(6,7-Dimethoxyquinazolin-4-yl)oxy-N,2-dimethyl-1-benzofuran-3-carboxamide<br></br>Molecular weight: 393.40<br></br>Formula: C21H19N3O4 <br></br>Solubility: DMSO (5 mg/ml)<br></br>Physical Properties: White soliod<br></br>Purity: 98% by HPLC NMR (Conforms)
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.