bs-83011C
[Life Science]
IPA-3
DATASHEET
Formulation Orange-yellow solid
Storage: -20°C
Product Information:
IPA-3 is a selective allosteric inhibitor of Group 1 p21-activated kinase (PAK1 IC50 = 2.5 µM)1 via covalent binding to the PAK1 regulatory domain preventing binding to the upstream activator Cdc422. IPA-3 has been shown to induce cell death in human leukemic cell lines3, significantly inhibit TGFβ1-induced prostate cell epithelial to mesenchymal transition4 and inhibits the growth of liver cancer cells5.
Description:
CAS Number: 42521-82-4<br></br>Chemical Name: 1,1'-Dithiodi-2-naphthol<br></br>Molecular weight: 350.45<br></br>Formula: C20H14O2S2<br></br>Solubility: DMSO (25 mg/ml)<br></br>Physical Properties: Yellow solid<br></br>Purity: 98% by TLC (methylene chloride; Rf=0.75) NMr (Conforms)
Size: 10 mg, 50 mg10 mg, 50 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.