bs-83006C
[Life Science]
Ipatasertib
DATASHEET
Formulation Beige solid
Storage: -20°C
Product Information:
Ipatasertib is a selective (against a panel of 230 kinases) and potent pan-Akt inhibitor (IC50s: Akt1 = 5 nM, Akt2 = 18 nM, Akt3 = 8 nM).1 It displayed efficacy in xenograft models of prostate, breast, ovarian, colorectal, non-small cell lung, glioblastoma, and melanoma cancers.2 In clinical trials.
Description:
CAS Number: 1001264-89-6<br></br>Chemical Name: (2S)-2-(4-Chlorophenyl)-1-[4-[(5R,7R)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl]piperazin-1-yl]-3-(propan-2-yla,ino)propan-1-one<br></br>Molecular weight: 458.00<br></br>Formula: C24H32ClN5O2 <br></br>Solubility: DMSO (25 mg/ml) Ethanol (20 mg/ml)<br></br>Physical Properties: Off-white of pale pink solid<br></br>Purity: 98% by HPLC NMR (Conforms)
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.