bs-83004C
[Life Science]
CB-103
DATASHEET
Formulation Pale yellow solid
Storage: RT
Product Information:
Orally active inhibitor of the Notch signaling activation complex (IC50’s from 0.9 to 3.9 µM in various cell-based assays), the most downstream level of the Notch signaling pathway. It inhibited the growth of Notch-addicted human T cell acute lymphoblastic leukemia cells as well as other cell lines. CB-103 also inhibited the growth of human breast cancer and leukemia xenografts without the intestinal toxicity associated with γ-secretase Notch inhibitors.
Description:
CAS Number: 218457-67-1<br></br>Chemical Name: 5-Amino-2-(4-tert-butylphenoxy)pyridine<br></br>Molecular weight: 242.32<br></br>Formula: C15H18N2O<br></br>Solubility: DMSO (>30 mg/ml)<br></br>Physical Properties: Off-white to pale orange solid<br></br>Purity: 98% by HPLC, NMR (Conforms)
Size: 20 mg, 100 mg20 mg, 100 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.