DATASHEET
Formulation
Off-white solid
Storage:
-20°C
Product Information:
BT2 is an inhibitor of the mitochondrial branched-chain α-ketoacid dehydrogenase complex kinase (BCKDC) - IC50 = 3.19 µM.1 Inhibition of this kinase has been shown to reduce levels of branched-chain amino acid concentrations in vivo. BT2 has also been shown to be a moderate inhibitor (Ki = 59 µM) of myeloid cell leukemia 1(Mcl 1), a Bcl-2 family protein.2
Description:
CAS Number: 34576-94-8<br></br>Chemical Name: 3,6-Dichlorobenzo[b]thiophene-2-carboxylic acid<br></br>Molecular weight: 247.10<br></br>Formula: C9H4Cl2O2S<br></br>Solubility: DMSO (>20 mg/ml)<br></br>Physical Properties: Off-white solid<br></br>Purity: 95% by TLC NMR (Conforms)