bs-82999C
[Life Science]
KC7F2
DATASHEET
Formulation White solid
Storage: -20°C
Product Information:
KC7F2 is an inhibitor of HIF-1α (IC50 = 20 µM).1 It inhibited HIF-mediated transcription in cells derived from glioma, breast, and prostate cancers. The mechanism of action of KC7F2 is via down-regulation of HIF-1α protein synthesis accompanied by suppression of phosphorylation of eukaryotic translation initiation factor 4E binding protein 1 and p70 S6 kinase, key regulators of HIF-1α protein synthesis.
Description:
CAS Number: 927822-86-4<br></br>Chemical Name: N,N'-(Dithiodi-2,1-ethanediyl)bis[2,5-dichlorobenzenesulfonamide<br></br>Molecular weight: 570.38<br></br>Formula: C16H16Cl4N2O4S4<br></br>Solubility: DMSO (>25 mg/ml)<br></br>Physical Properties: Off-white solid<br></br>Purity: 98% by HPLC, NMR (Conforms)
Size: 50mg,10mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.