bs-82989C
[Life Science]
BO-264
DATASHEET
Formulation Off-white solid
Storage: -20°C
Product Information:
BO-264 is a potent (IC50 = 188 nM) inhibitor of transforming acidic coiled-coil 3 (TACC3), an important protein involved in microtubule stability and centrosome integrity.1 TACC3 is frequently upregulated in a broad range of cancers. BO-264 displayed significant anticancer activity in greater than 90% of cell lines in the NCI-60 human cancer cell line panel. Active in vivo in mice injected with JIMT-1 and EMT6 breast cancer cells as well as mouse colon cancer xenografts HCT-116 and CT-26.
Description:
CAS Number: 2408648-20-2<br></br>Chemical Name: 3-(4-Methoxyphenyl)-N-(2-morpholin-4-ylpyrimidin-4-yl)-1,2-oxazol-5-amine<br></br>Molecular weight: 353.38<br></br>Formula: C18H19N5O3 <br></br>Solubility: DMSO (>25 mg/ml)<br></br>Physical Properties: Off-white solid<br></br>Purity: 99% by HPLC NMR (Conforms)
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.